Rectal invasion worse prognostic factor than bladder invasion in advanced cervical cancer

• Patients with stage IVA cervical cancer have a poor prognosis, with 5-y survival of only 24%, and rectal invasion might be a worse prognostic factor than bladder invasion.

Study design

• Retrospective review of 67 patients treated with definitive photon radiation therapy for pathologically proven stage IVA cervical cancer between 1980 and 2010.
• 53 patients were stage IVA on the basis of bladder invasion, 7 according to rectal mucosal invasion, and 7 because of both bladder and rectal mucosal invasion.

[Source:- Univadis]