Takeaway Overall survival was similar in patients receiving chemotherapy following radium-223 and placebo, irrespective of prior docetaxel use. Chemotherapy was well-tolerated in patients who had previously received radium-223. Key results 142 radium-223 and 64 placebo patients received subsequent chemotherapy, most commonly docetaxel (70% radium-223 vs 72% placebo) and mitoxantrone (16% ... Read More »